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PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth
Phosphatases of regenerating liver (PRLs) are markers of cancer and promote tumor growth. They have been implicated in a variety of biochemical pathways but the physiologically relevant target of phosphatase activity has eluded 20 years of investigation. Here, we show that PRL3 catalytic activity is...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7450121/ https://ncbi.nlm.nih.gov/pubmed/32571875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014464 |
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