The cyclic nucleotide–binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg(2+) efflux activity

Proteins of the cyclin M family (CNNMs; also called ancient conserved domain proteins, or ACDPs) are represented by four integral membrane proteins that have been proposed to function as Mg(2+) transporters. CNNMs are associated with a number of genetic diseases affecting ion movement and cancer via...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Chen, Yu Seby, Kozlov, Guennadi, Fakih, Rayan, Funato, Yosuke, Miki, Hiroaki, Gehring, Kalle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2018
Pynciau:
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Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311497/
https://ncbi.nlm.nih.gov/pubmed/30341174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005672
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