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The cyclic nucleotide–binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg(2+) efflux activity
Proteins of the cyclin M family (CNNMs; also called ancient conserved domain proteins, or ACDPs) are represented by four integral membrane proteins that have been proposed to function as Mg(2+) transporters. CNNMs are associated with a number of genetic diseases affecting ion movement and cancer via...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6311497/ https://ncbi.nlm.nih.gov/pubmed/30341174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005672 |
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