T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4

T cell-mediated immunity is governed primarily by T cell receptor (TCR) recognition of peptide-human leukocyte antigen (pHLA) complexes and is essential for immunosurveillance and disease control. This interaction is generally stabilized by interactions between the HLA surface and TCR germline-encod...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Coles, Charlotte H., McMurran, Catriona, Lloyd, Angharad, Hock, Miriam, Hibbert, Linda, Raman, Marine C. C., Hayes, Conor, Lupardus, Patrick, Cole, David K., Harper, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450119/
https://ncbi.nlm.nih.gov/pubmed/32532817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014016
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