HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway

Rationale: It is known that neuroinflammation plays a critical and detrimental role in the development of cerebral ischemia/reperfusion (I/R), but the regulation of the cyclic GMP-AMP synthase (cGAS)-mediated innate immune response in I/R-induced neuroinflammation is largely unexplored. This study a...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Liao, Yajin, Cheng, Jinbo, Kong, Xiangxi, Li, Shuoshuo, Li, Xiaoheng, Zhang, Meijuan, Zhang, He, Yang, Tianli, Dong, Yuan, Li, Jun, Xu, Yun, Yuan, Zengqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449914/
https://ncbi.nlm.nih.gov/pubmed/32863951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47651
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