Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma

Minimal residual disease (MRD) tracking by next generation sequencing of immunoglobulin sequences is moving towards clinical implementation in multiple myeloma. However, there is only sparse information available to address whether clonal sequences remain stable for tracking over time, and to what e...

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Published in:Am J Hematol
Main Authors: Rustad, Even H, Misund, Kristine, Bernard, Elsa, Coward, Eivind, Yellapantula, Venkata D, Hultcrantz, Malin, Ho, Caleb, Kazandjian, Dickran, Korde, Neha, Mailankody, Sham, Keats, Jonathan J, Akhlaghi, Theresia, Viny, Aaron D, Mayman, David J, Carroll, Kaitlin, Patel, Minal, Famulare, Christopher A, Bruinink, Davine Hofste op, Hutt, Kasey, Jacobsen, Austin, Huang, Ying, Miller, Jeffrey E, Maura, Francesco, Papaemmanuil, Elli, Waage, Anders, Arcila, Maria E, Landgren, Ola
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449571/
https://ncbi.nlm.nih.gov/pubmed/31571261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25641
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