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Metformin Suppresses Development of the Echinococcus multilocularis Larval Stage by Targeting the TOR Pathway

Alveolar echinococcosis (AE) is a severe disease caused by the larval stage of the tapeworm Echinococcus multilocularis. Current chemotherapeutic treatment options based on benzimidazoles are of limited effectiveness, which underlines the need to find new antiechinococcosis drugs. Metformin is an an...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Loos, Julia A., Dávila, Valeria A., Brehm, Klaus, Cumino, Andrea C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449199/
https://ncbi.nlm.nih.gov/pubmed/32540980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01808-19
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