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Metformin Suppresses Development of the Echinococcus multilocularis Larval Stage by Targeting the TOR Pathway

Alveolar echinococcosis (AE) is a severe disease caused by the larval stage of the tapeworm Echinococcus multilocularis. Current chemotherapeutic treatment options based on benzimidazoles are of limited effectiveness, which underlines the need to find new antiechinococcosis drugs. Metformin is an an...

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發表在:Antimicrob Agents Chemother
Main Authors: Loos, Julia A., Dávila, Valeria A., Brehm, Klaus, Cumino, Andrea C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449199/
https://ncbi.nlm.nih.gov/pubmed/32540980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01808-19
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