Nonstationary Pharmacokinetics of Caspofungin in ICU Patients

Standard dosing of caspofungin in critically ill patients has been reported to result in lower drug exposure, which can lead to subtherapeutic 24-h area under the curve to MIC (AUC(0–24)/MIC) ratios. The aim of the study was to investigate the population pharmacokinetics of caspofungin in a cohort o...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Borsuk-De Moor, Agnieszka, Sysiak-Sławecka, Justyna, Rypulak, Elżbieta, Borys, Michał, Piwowarczyk, Paweł, Raszewski, Grzegorz, Onichimowski, Dariusz, Czuczwar, Mirosław, Wiczling, Paweł
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449161/
https://ncbi.nlm.nih.gov/pubmed/32601169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00345-20
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