Population Pharmacokinetics of High-Dose Tigecycline in Patients with Sepsis or Septic Shock

Tigecycline is a glycylcycline often used in critically ill patients as the antibiotic of last resort. The pharmacokinetics (PK) of tigecycline in intensive care unit (ICU) patients can be affected by severe pathophysiological changes so that standard dosing might not be adequate. The aim of this st...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Borsuk-De Moor, Agnieszka, Rypulak, Elżbieta, Potręć, Beata, Piwowarczyk, Paweł, Borys, Michał, Sysiak, Justyna, Onichimowski, Dariusz, Raszewski, Grzegorz, Czuczwar, Mirosław, Wiczling, Paweł
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913959/
https://ncbi.nlm.nih.gov/pubmed/29358291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02273-17
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