Population Pharmacokinetics of High-Dose Tigecycline in Patients with Sepsis or Septic Shock

Tigecycline is a glycylcycline often used in critically ill patients as the antibiotic of last resort. The pharmacokinetics (PK) of tigecycline in intensive care unit (ICU) patients can be affected by severe pathophysiological changes so that standard dosing might not be adequate. The aim of this st...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Borsuk-De Moor, Agnieszka, Rypulak, Elżbieta, Potręć, Beata, Piwowarczyk, Paweł, Borys, Michał, Sysiak, Justyna, Onichimowski, Dariusz, Raszewski, Grzegorz, Czuczwar, Mirosław, Wiczling, Paweł
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913959/
https://ncbi.nlm.nih.gov/pubmed/29358291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02273-17
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