Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors

Enterovirus A71 (EV-A71), a positive-stranded RNA virus of the Picornaviridae family, may cause neurological complications or fatality in children. We examined specific factors responsible for this virulence using a chemical genetics approach. Known compounds from an anti-EV-A71 herbal medicine, Sal...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Hsieh, Chung-Fan, Jheng, Jia-Rong, Lin, Guan-Hua, Chen, Yu-Li, Ho, Jin-Yuan, Liu, Chien-Jou, Hsu, Kuei-Yang, Chen, Yuan-Siao, Chan, Yoke Fun, Yu, Hui-Ming, Hsieh, Pei-Wen, Chern, Jyh-Haur, Horng, Jim-Tong
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448925/
https://ncbi.nlm.nih.gov/pubmed/32397909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1767512
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