Clinical Relevance of an Amplicon-Based Liquid Biopsy for Detecting ALK and ROS1 Fusion and Resistance Mutations in Patients With Non–Small-Cell Lung Cancer

PURPOSE: Liquid biopsy specimen genomic profiling is integrated in non–small-cell lung cancer (NSCLC) guidelines; however, data on the clinical relevance for ALK/ROS1 alterations are scarce. We evaluated the clinical utility of a targeted amplicon-based assay in a large prospective cohort of patient...

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Detalhes bibliográficos
Publicado no:JCO Precis Oncol
Main Authors: Mezquita, Laura, Swalduz, Aurélie, Jovelet, Cécile, Ortiz-Cuaran, Sandra, Howarth, Karen, Planchard, David, Avrillon, Virginie, Recondo, Gonzalo, Marteau, Solène, Benitez, Jose Carlos, De Kievit, Frank, Plagnol, Vincent, Lacroix, Ludovic, Odier, Luc, Rouleau, Etienne, Fournel, Pierre, Caramella, Caroline, Tissot, Claire, Adam, Julien, Woodhouse, Samuel, Nicotra, Claudio, Auclin, Edouard, Remon, Jordi, Morris, Clive, Green, Emma, Massard, Christophe, Pérol, Maurice, Friboulet, Luc, Besse, Benjamin, Saintigny, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2020
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448797/
https://ncbi.nlm.nih.gov/pubmed/32923908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.19.00281
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