Photoswitchable affinity reagents: Computational design and efficient red-light switching

Photo-controlled affinity reagents seek to provide modular spatiotemporal control of bioactivity by conferring photo-switchability of function on an affinity reagent scaffold. Here we used Rosetta-based computational methods to screen for sites on the Fynomer affinity reagent structure for attachmen...

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Publicat a:ChemPhotoChem
Autors principals: Yasuike, Nobuo, Blacklock, Kristin M., Lu, Huixin, Jaikaran, Anna S.I., McDonald, Sherin, Uppalapati, Maruti, Khare, Sagar D., Woolley, G. Andrew
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448683/
https://ncbi.nlm.nih.gov/pubmed/32856001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptc.201900016
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