Flagellin shifts 3D bronchospheres towards mucus hyperproduction

Cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are associated with acute and chronic bacterial infections of the lung. Excessive differentiation of basal cells to mucus-producing goblet cells can result in mucus hyperproduction and loss of mucociliary clearance in the airways...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Sprott, Richard F., Ritzmann, Felix, Langer, Frank, Yao, Yiwen, Herr, Christian, Kohl, Yvonne, Tschernig, Thomas, Bals, Robert, Beisswenger, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448433/
https://ncbi.nlm.nih.gov/pubmed/32847538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01486-x
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