Mycobacterium tuberculosis Rv0991c Is a Redox-Regulated Molecular Chaperone

The bacterial pathogen Mycobacterium tuberculosis is the leading cause of death by an infectious disease among humans. Here, we describe a previously uncharacterized M. tuberculosis protein, Rv0991c, as a molecular chaperone that is activated by oxidation. Rv0991c has homologs in most bacterial line...

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Bibliographic Details
Published in:mBio
Main Authors: Becker, Samuel H., Ulrich, Kathrin, Dhabaria, Avantika, Ueberheide, Beatrix, Beavers, William, Skaar, Eric P., Iyer, Lakshminarayan M., Aravind, L., Jakob, Ursula, Darwin, K. Heran
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448276/
https://ncbi.nlm.nih.gov/pubmed/32843553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01545-20
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