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Twist1-induced epithelial dissemination requires Prkd1 signaling

Dissemination is an essential early step in metastasis but its molecular basis remains incompletely understood. To define the essential targetable effectors of this process, we developed a 3D mammary epithelial culture model, in which dissemination is induced by overexpression of the transcription f...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Georgess, Dan, Padmanaban, Veena, Sirka, Orit Katarina, Coutinho, Kester, Choi, Alex, Frid, Gabriela, Neumann, Neil M., Inoue, Takanari, Ewald, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7448227/
https://ncbi.nlm.nih.gov/pubmed/31676574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3241
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