Twist1-induced dissemination preserves epithelial identity and requires E-cadherin

Dissemination of epithelial cells is a critical step in metastatic spread. Molecular models of dissemination focus on loss of E-cadherin or repression of cell adhesion through an epithelial to mesenchymal transition (EMT). We sought to define the minimum molecular events necessary to induce dissemin...

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Autores principales: Shamir, Eliah R., Pappalardo, Elisa, Jorgens, Danielle M., Coutinho, Kester, Tsai, Wen-Ting, Aziz, Khaled, Auer, Manfred, Tran, Phuoc T., Bader, Joel S., Ewald, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941052/
https://ncbi.nlm.nih.gov/pubmed/24590176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201306088
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