Chemoenzymatic synthesis of daptomycin analogs active against daptomycin-resistant strains

ABSTRACT: Daptomycin is a last resort antibiotic for the treatment of infections caused by many Gram-positive bacterial strains, including vancomycin-resistant Enterococcus (VRE) and methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA). However, the emergence of daptomycin-res...

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Detalhes bibliográficos
Publicado no:Appl Microbiol Biotechnol
Main Authors: Scull, Erin M., Bandari, Chandrasekhar, Johnson, Bryce P., Gardner, Eric D., Tonelli, Marco, You, Jianlan, Cichewicz, Robert H., Singh, Shanteri
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Biotechnologically Relevant Enzymes and Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447621/
https://ncbi.nlm.nih.gov/pubmed/32725322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-020-10790-x
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