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CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles
Ca(2+)/calmodulin-dependent kinase II (CaMKII) regulates synaptic plasticity in multiple ways, supposedly including the secretion of neuromodulators like brain-derived neurotrophic factor (BDNF). Here, we show that neuromodulator secretion is indeed reduced in mouse α- and βCaMKII-deficient (αβCaMKI...
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| Publicado en: | PLoS Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7447270/ https://ncbi.nlm.nih.gov/pubmed/32776935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000826 |
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