Cargando...

Kinase activity is not required for αCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses

Using targeted mouse mutants and pharmacologic inhibition of αCaMKII, we demonstrate that the αCaMKII protein, but not its activation, autophosphorylation or its ability to phosphorylate synapsin I, is required for normal short-term presynaptic plasticity. Furthermore, αCaMKII regulates the number o...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hojjati, Mohammad Reza, van Woerden, Geeske M, Tyler, William J, Giese, Karl Peter, Silva, Alcino J, Pozzo-Miller, Lucas, Elgersma, Ype
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804046/
https://ncbi.nlm.nih.gov/pubmed/17660813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1946
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!