Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program

BACKGROUND & AIMS: Given ongoing challenges in non-invasive non-alcoholic liver disease (NAFLD) diagnosis, we sought to validate an ALT-based NAFLD phenotype using measures readily available in electronic health records (EHRs) and population-based studies by leveraging the clinical and genetic d...

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Udgivet i:PLoS One
Main Authors: Serper, Marina, Vujkovic, Marijana, Kaplan, David E., Carr, Rotonya M., Lee, Kyung Min, Shao, Qing, Miller, Donald R., Reaven, Peter D., Phillips, Lawrence S., O’Donnell, Christopher J., Meigs, James B., Wilson, Peter W. F., Vickers-Smith, Rachel, Kranzler, Henry R., Justice, Amy C., Gaziano, John M., Muralidhar, Sumitra, Pyarajan, Saiju, DuVall, Scott L., Assimes, Themistocles L., Lee, Jennifer S., Tsao, Philip S., Rader, Daniel J., Damrauer, Scott M., Lynch, Julie A., Saleheen, Danish, Voight, Benjamin F., Chang, Kyong-Mi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447043/
https://ncbi.nlm.nih.gov/pubmed/32841307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237430
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