Exploratory Analysis of Single-Gene Predictive Biomarkers in HERA DASL Cohort Reveals That C8A mRNA Expression Is Prognostic of Outcome and Predictive of Benefit of Trastuzumab

PURPOSE: The Herceptin Adjuvant study is an international multicenter randomized trial that compared 1 or 2 years of trastuzumab given every 3 weeks with observation in women with human epidermal growth factor 2–positive (HER2+) breast cancer after chemotherapy. Identification of biomarkers predicti...

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Publicat a:JCO Precis Oncol
Autors principals: Willis, Scooter, Polydoropoulou, Varvara, Sun, Yuliang, Young, Brandon, Tsourti, Zoi, Karlis, Dimitris, Long, Bradley, Lin, Xiaoqian, Theel, Stephanie, Carlson, Jennifer, Győrffy, Balazs, Williams, Casey, Abramovitz, Mark, Dafni, Urania, Dowsett, Mitch, Leyland-Jones, Brian
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2018
Matèries:
Original Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446467/
https://ncbi.nlm.nih.gov/pubmed/32913993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00016
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