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Early-Phase Platform Trials: A New Paradigm for Dose Finding and Treatment Screening in the Era of Precision Oncology

Applications in early-phase cancer trials have motivated the development of many statistical designs since the late 1980s, including dose-finding methods, futility screening, treatment selection, and early stopping rules. These methods are often proposed to address the conventional cytotoxic therape...

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Detalhes bibliográficos
Publicado no:JCO Precis Oncol
Main Authors: Polley, Mei-Yin C., Cheung, Ying Kuen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446322/
https://ncbi.nlm.nih.gov/pubmed/32923846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.19.00057
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