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The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome
Dramatic cardiomegaly arising from gain-of-function (GoF) mutations in the ATP-sensitive potassium (K(ATP)) channels genes, ABCC9 and KCNJ8, is a characteristic feature of Cantú syndrome (CS). How potassium channel over-activity results in cardiac hypertrophy, as well as the long-term consequences o...
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| Опубликовано в: : | Function (Oxf) |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7446247/ https://ncbi.nlm.nih.gov/pubmed/32865539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/function/zqaa004 |
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