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Radiobiologically derived biphasic fractionation schemes to overcome the effects of tumour hypoxia

OBJECTIVE: As a fractionated course of radiotherapy proceeds tumour shrinkage leads to resolution of hypoxia and the initiation of accelerated proliferation of radioresistant cancer cells with better repair capacity. We hypothesise that, in tumours with significant hypoxia, improved tumour control c...

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Bibliografski detalji
Izdano u:Br J Radiol
Glavni autori: Joseph, Nuradh, Kirkby, Norman F., Hoskin, Peter J, West, Catharine M L, Choudhury, Ananya, Dale, Roger G.
Format: Artigo
Jezik:Inglês
Izdano: The British Institute of Radiology. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446001/
https://ncbi.nlm.nih.gov/pubmed/32462907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20190250
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