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Radiobiologically derived biphasic fractionation schemes to overcome the effects of tumour hypoxia

OBJECTIVE: As a fractionated course of radiotherapy proceeds tumour shrinkage leads to resolution of hypoxia and the initiation of accelerated proliferation of radioresistant cancer cells with better repair capacity. We hypothesise that, in tumours with significant hypoxia, improved tumour control c...

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Detalles Bibliográficos
Publicado en:Br J Radiol
Main Authors: Joseph, Nuradh, Kirkby, Norman F., Hoskin, Peter J, West, Catharine M L, Choudhury, Ananya, Dale, Roger G.
Formato: Artigo
Idioma:Inglês
Publicado: The British Institute of Radiology. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446001/
https://ncbi.nlm.nih.gov/pubmed/32462907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20190250
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