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Radiobiologically derived biphasic fractionation schemes to overcome the effects of tumour hypoxia

OBJECTIVE: As a fractionated course of radiotherapy proceeds tumour shrinkage leads to resolution of hypoxia and the initiation of accelerated proliferation of radioresistant cancer cells with better repair capacity. We hypothesise that, in tumours with significant hypoxia, improved tumour control c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Radiol
Hauptverfasser: Joseph, Nuradh, Kirkby, Norman F., Hoskin, Peter J, West, Catharine M L, Choudhury, Ananya, Dale, Roger G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The British Institute of Radiology. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446001/
https://ncbi.nlm.nih.gov/pubmed/32462907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20190250
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