Ischemia reperfusion injury provokes adverse left ventricular remodeling in dysferlin-deficient hearts through a pathway that involves TIRAP dependent signaling

Cardiac myocytes have multiple cell autonomous mechanisms that facilitate stabilization and repair of damaged sarcolemmal membranes following myocardial injury. Dysferlin is a protein which facilitates membrane repair by promoting membrane resealing. Although prior studies have shown that dysferlin-...

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Publicado no:Sci Rep
Main Authors: Evans, Sarah, Weinheimer, Carla J., Kovacs, Attila, Williams, Jesse W., Randolph, Gwendalyn J., Jiang, Wenlong, Barger, Philip M., Mann, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445276/
https://ncbi.nlm.nih.gov/pubmed/32839504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71079-7
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