Tumor Necrosis Factor Receptor Associated Factor 2 Signaling Provokes Adverse Cardiac Remodeling in the Adult Mammalian Heart

BACKGROUND: Tumor necrosis factor (TNF) superfamily ligands that provoke a dilated cardiac phenotype signal through a common scaffolding protein termed TNF receptor associated factor 2 (TRAF2); however, virtually nothing is known with regard to TRAF2 signaling in the adult mammalian heart. METHODS A...

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Bibliographic Details
Main Authors: Divakaran, Vijay G., Evans, Sarah, Topkara, Veli K., Diwan, Abhinav, Burchfield, Jana, Gao, Feng, Dong, Jianwen, Tzeng, Huei-Ping, Sivasubramanian, Natarajan, Barger, Philip M., Mann, Douglas L.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672470/
https://ncbi.nlm.nih.gov/pubmed/23493088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.000080
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