Acapsular Staphylococcus aureus with a non-functional agr regains capsule expression after passage through the bloodstream in a bacteremia mouse model

Selection pressures exerted on Staphylococcus aureus by host factors during infection may lead to the emergence of regulatory phenotypes better adapted to the infection site. Traits convenient for persistence may be fixed by mutation thus turning these mutants into microevolution endpoints. The feas...

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Udgivet i:Sci Rep
Main Authors: Suligoy, Carlos M., Díaz, Rocío E., Gehrke, Ana-Katharina, Ring, Natalie, Yebra, Gonzalo, Alves, Joana, Gómez, Marisa I., Wendler, Sindy, FITZGERALD, J. Ross, Tuchscherr, Lorena, Löffler, Bettina, Sordelli, Daniel O., Llana, Mariángeles Noto, Buzzola, Fernanda R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445255/
https://ncbi.nlm.nih.gov/pubmed/32839485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70671-1
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