Acapsular Staphylococcus aureus with a non-functional agr regains capsule expression after passage through the bloodstream in a bacteremia mouse model

Selection pressures exerted on Staphylococcus aureus by host factors during infection may lead to the emergence of regulatory phenotypes better adapted to the infection site. Traits convenient for persistence may be fixed by mutation thus turning these mutants into microevolution endpoints. The feas...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Suligoy, Carlos M., Díaz, Rocío E., Gehrke, Ana-Katharina, Ring, Natalie, Yebra, Gonzalo, Alves, Joana, Gómez, Marisa I., Wendler, Sindy, FITZGERALD, J. Ross, Tuchscherr, Lorena, Löffler, Bettina, Sordelli, Daniel O., Llana, Mariángeles Noto, Buzzola, Fernanda R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445255/
https://ncbi.nlm.nih.gov/pubmed/32839485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70671-1
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