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Olfactory receptor 78 participates in carotid body response to a wide range of low O(2) levels but not severe hypoxia

The role of olfactory receptor 78 (Olfr78) in carotid body (CB) response to hypoxia was examined. BL6 mice with global deletion of Olfr78 manifested an impaired hypoxic ventilatory response (HVR), a hallmark of the CB chemosensory reflex, CB sensory nerve activity, and reduced intracellular Ca(2+) c...

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Detalles Bibliográficos
Publicado en:J Neurophysiol
Main Authors: Peng, Ying-Jie, Gridina, Anna, Wang, Benjamin, Nanduri, Jayasri, Fox, Aaron P., Prabhakar, Nanduri R.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444916/
https://ncbi.nlm.nih.gov/pubmed/32208891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00075.2020
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