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Olfactory receptor 78 participates in carotid body response to a wide range of low O(2) levels but not severe hypoxia

The role of olfactory receptor 78 (Olfr78) in carotid body (CB) response to hypoxia was examined. BL6 mice with global deletion of Olfr78 manifested an impaired hypoxic ventilatory response (HVR), a hallmark of the CB chemosensory reflex, CB sensory nerve activity, and reduced intracellular Ca(2+) c...

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Dettagli Bibliografici
Pubblicato in:J Neurophysiol
Autori principali: Peng, Ying-Jie, Gridina, Anna, Wang, Benjamin, Nanduri, Jayasri, Fox, Aaron P., Prabhakar, Nanduri R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444916/
https://ncbi.nlm.nih.gov/pubmed/32208891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00075.2020
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