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Chimeric antigen receptor T‐cell therapies: Optimising the dose
Lymphocytes such as T‐cells can be genetically transduced to express a synthetic chimeric antigen receptor (CAR) that re‐directs their cytotoxic activity against a tumour‐expressed antigen of choice. Autologous (patient‐derived) CAR T‐cells have been licensed to treat certain relapsed and refractory...
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| Publicado no: | Br J Clin Pharmacol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7444796/ https://ncbi.nlm.nih.gov/pubmed/32175617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14281 |
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