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Optimization of a β-sheet-cap for long loop closure

Protein loops make up a large portion of the secondary structure in nature. But very little is known concerning loop closure dynamics and the effects of loop composition on fold stability. We have designed a small system with stable β-sheet structures, including features that allow us to probe these...

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Vydáno v:Biopolymers
Hlavní autoři: Anderson, Jordan M., Shcherbakov, Alexander A., Kier, Brandon L., Kellock, Jackson, Shu, Irene, Byrne, Aimee L., Eidenschink, Lisa A., Andersen, Niels H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444092/
https://ncbi.nlm.nih.gov/pubmed/27701729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22995
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