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NFAT5, which protects against hypertonicity, is activated by that stress via structuring of its intrinsically disordered domain
Nuclear Factor of Activated T cells 5 (NFAT5) is a transcription factor (TF) that mediates protection from adverse effects of hypertonicity by increasing transcription of genes, including those that lead to cellular accumulation of protective organic osmolytes. NFAT5 has three intrinsically ordered...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7443939/ https://ncbi.nlm.nih.gov/pubmed/32747529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911680117 |
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