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NFAT5, which protects against hypertonicity, is activated by that stress via structuring of its intrinsically disordered domain

Nuclear Factor of Activated T cells 5 (NFAT5) is a transcription factor (TF) that mediates protection from adverse effects of hypertonicity by increasing transcription of genes, including those that lead to cellular accumulation of protective organic osmolytes. NFAT5 has three intrinsically ordered...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Kumar, Raj, DuMond, Jenna F., Khan, Shagufta H., Thompson, E. Brad, He, Yi, Burg, Maurice B., Ferraris, Joan D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443939/
https://ncbi.nlm.nih.gov/pubmed/32747529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911680117
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