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Differences in the free energies between the excited states of Aβ40 and Aβ42 monomers encode their aggregation propensities
The early events in the aggregation of the intrinsically disordered peptide, amyloid- [Formula: see text] (A [Formula: see text]), involve transitions from the disordered free energy ground state to assembly-competent states. Are the fingerprints of order found in the amyloid fibrils encoded in the...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7443889/ https://ncbi.nlm.nih.gov/pubmed/32732434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002570117 |
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