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Interleukin-1 receptor antagonist enhances chemosensitivity to fluorouracil in treatment of Kras mutant colon cancer

BACKGROUND: Kras mutant colon cancer shows abnormal activation of the nuclear factor kappa-B (NF-κB) pathway, resulting in the proliferation of tumor cells. Treatment with fluorouracil (5-FU) might not achieve the expected inhibition of proliferation of malignant cells based on the fluorouracil-indu...

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Bibliografske podrobnosti
izdano v:World J Gastrointest Oncol
Main Authors: Yan, Yan, Lin, Hong-Wei, Zhuang, Zhuo-Nan, Li, Ming, Guo, Sen
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443842/
https://ncbi.nlm.nih.gov/pubmed/32879665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4251/wjgo.v12.i8.877
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