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Oral 25-Hydroxycholecalciferol Acts as an Agonist in the Duodenum of Mice and as Modeled in Cultured Human HT-29 and Caco2 Cells

BACKGROUND: 25-Hydroxycholecalciferol [25(OH)D] is the predominant circulating metabolite of vitamin D and serves as the precursor for 1α,25-dihydroxycholecalciferol [1,25(OH)(2)D], the hormonally active form. The presence of 1α-hydroxylase (1α-OHase) in the intestine suggests that 1,25(OH)(2)D can...

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Bibliografiske detaljer
Udgivet i:J Nutr
Main Authors: Reynolds, Carmen J, Koszewski, Nicholas J, Horst, Ronald L, Beitz, Donald C, Goff, Jesse P
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443726/
https://ncbi.nlm.nih.gov/pubmed/31665381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jn/nxz261
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