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Importance of apical membrane delivery of 1,25-dihydroxyvitamin D(3) to vitamin D-responsive gene expression in the colon
Synthetic conjugation of a glucuronide to 1,25-dihydroxyvitamin D(3) (1,25D(3)) to produce β-25-monoglucuronide-1,25D(3) (βGluc-1,25D(3)) renders the hormone biologically inactive and resistant to mammalian digestive enzymes. However, β-glucuronidase produced by bacteria in the lower intestinal trac...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347747/ https://ncbi.nlm.nih.gov/pubmed/22837344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00149.2012 |
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