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Excellent Response to Olaparib in a Patient with Metastatic Pancreatic Adenocarcinoma with Germline BRCA1 Mutation after Progression on FOLFIRINOX: Case Report and Literature Review

Metastatic pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. Until recently, cytotoxic chemotherapy was the only treatment option. Currently, there are subgroups of patients with PDAC either with somatic or germline mutations who are candidates for targeted agents. Germline mutations i...

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Detalhes bibliográficos
Publicado no:Case Rep Oncol
Main Authors: Pimenta, Jefferson Rios, Ueda, Serli Kiyomi Nakao, Peixoto, Renata D'Alpino
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443654/
https://ncbi.nlm.nih.gov/pubmed/32884538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000508533
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