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Excellent Response to Olaparib in a Patient with Metastatic Pancreatic Adenocarcinoma with Germline BRCA1 Mutation after Progression on FOLFIRINOX: Case Report and Literature Review

Metastatic pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. Until recently, cytotoxic chemotherapy was the only treatment option. Currently, there are subgroups of patients with PDAC either with somatic or germline mutations who are candidates for targeted agents. Germline mutations i...

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Dettagli Bibliografici
Pubblicato in:Case Rep Oncol
Autori principali: Pimenta, Jefferson Rios, Ueda, Serli Kiyomi Nakao, Peixoto, Renata D'Alpino
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443654/
https://ncbi.nlm.nih.gov/pubmed/32884538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000508533
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