The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4

The supplementation of royal jelly (RJ) is known to provide a variety of health benefits, including anti-inflammatory and anti-obesity effects. RJ treatment also reportedly protects against bone loss, but no single factor in RJ has yet been identified as an anti-osteoporosis agent. Here we fractiona...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Tsuchiya, Yosuke, Hayashi, Mikihito, Nagamatsu, Katashi, Ono, Takehito, Kamakura, Masaki, Iwata, Takanori, Nakashima, Tomoki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443481/
https://ncbi.nlm.nih.gov/pubmed/32647011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013821
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