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RANKL biology: bone metabolism, the immune system, and beyond

Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage–lineage cells into the bone–resorbing cells called osteoclasts. Because abnormalities in RANKL, its signaling receptor RANK, or decoy receptor osteoprotegerin (OPG) lead to bone diseases such as oste...

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Bibliografiske detaljer
Udgivet i:Inflamm Regen
Main Authors: Ono, Takehito, Hayashi, Mikihito, Sasaki, Fumiyuki, Nakashima, Tomoki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006158/
https://ncbi.nlm.nih.gov/pubmed/32047573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-019-0111-3
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