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The Alzheimer’s Disease “non-amyloidogenic” p3 peptide revisited: a case for Amyloid-α

Amyloid-β (Aβ) is an intrinsically disordered peptide thought to play an important role in Alzheimer’s Disease. It has been the target of most AD therapeutic efforts, which have repeatedly failed in clinical trials. A more predominant peptidic fragment, formed through alternative processing of the A...

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Bibliographische Detailangaben
Veröffentlicht in:ACS Chem Neurosci
Hauptverfasser: Kuhn, Ariel J., Abrams, Benjamin S., Knowlton, Stella, Raskatov, Jevgenij A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443049/
https://ncbi.nlm.nih.gov/pubmed/32412731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00160
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