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α‐Mangostin decreases β‐amyloid peptides production via modulation of amyloidogenic pathway

AIMS: β‐amyloid (Aβ) aggregation and deposition play a central role in the pathogenic process of Alzheimer's disease (AD). α‐Mangostin (α‐M), a polyphenolic xanthone, have been shown to dissociate Aβ oligomers. In this study, we further investigated the effect of α‐M on Aβ production and its mo...

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Bibliografiska uppgifter
I publikationen:CNS Neurosci Ther
Huvudupphovsmän: Zhao, Lan‐Xue, Wang, Yan, Liu, Ting, Wang, Yan‐Xia, Chen, Hong‐Zhuan, Xu, Jian‐Rong, Qiu, Yu
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492755/
https://ncbi.nlm.nih.gov/pubmed/28429536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12699
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