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Current strategies and opportunities to manufacture cells for modeling human lungs

Chronic lung diseases remain major healthcare burdens, for which the only curative treatment is lung transplantation. In vitro human models are promising platforms for identifying and testing novel compounds to potentially decrease this burden. Directed differentiation of pluripotent stem cells is a...

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Опубликовано в: :Adv Drug Deliv Rev
Главные авторы: Varma, Ratna, Soleas, John P., Waddell, Thomas K., Karoubi, Golnaz, McGuigan, Alison P.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier B.V. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442933/
https://ncbi.nlm.nih.gov/pubmed/32835746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2020.08.005
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