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Current strategies and opportunities to manufacture cells for modeling human lungs

Chronic lung diseases remain major healthcare burdens, for which the only curative treatment is lung transplantation. In vitro human models are promising platforms for identifying and testing novel compounds to potentially decrease this burden. Directed differentiation of pluripotent stem cells is a...

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Dettagli Bibliografici
Pubblicato in:Adv Drug Deliv Rev
Autori principali: Varma, Ratna, Soleas, John P., Waddell, Thomas K., Karoubi, Golnaz, McGuigan, Alison P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier B.V. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442933/
https://ncbi.nlm.nih.gov/pubmed/32835746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2020.08.005
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