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LncRNA CRNDE facilitates epigenetic suppression of CELF2 and LATS2 to promote proliferation, migration and chemoresistance in hepatocellular carcinoma

Our study aimed to investigate the expression, functional significance, and related mechanism of long noncoding RNA CRNDE (colorectal neoplasia differentially expressed) in hepatocellular carcinoma (HCC) pathogenesis. The resulted revealed that CRNDE was significantly overexpressed in HCC tissues an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Xie, Shu-Cai, Zhang, Jian-Quan, Jiang, Xi-Li, Hua, Yong-Yong, Xie, Shao-Wei, Qin, Ye-Ang, Yang, Yi-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442829/
https://ncbi.nlm.nih.gov/pubmed/32826865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02853-8
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