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The tumour microenvironment in pancreatic cancer — clinical challenges and opportunities

Metastatic pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumours despite the use of multi-agent conventional chemotherapy regimens. Such poor outcomes have fuelled ongoing efforts to exploit the tumour microenvironment (TME) for therapy, but strategies aimed at deconstructi...

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Detalhes bibliográficos
Publicado no:Nat Rev Clin Oncol
Main Authors: Ho, Won Jin, Jaffee, Elizabeth M., Zheng, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442729/
https://ncbi.nlm.nih.gov/pubmed/32398706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-020-0363-5
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