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Challenges and Opportunities for Pancreatic Cancer Immunotherapy

Pancreatic ductal adenocarcinoma (PDA) is among the most immune-resistant tumor types. Its unique genomic landscape shaped by oncogenic drivers promotes immune suppression from the earliest stages of tumor inception to subvert adaptive T-cell immunity. Single-agent immune modulators have thus far pr...

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書目詳細資料
發表在:Cancer Cell
Main Authors: Bear, Adham S., Vonderheide, Robert H., O’Hara, Mark H.
格式: Artigo
語言:Inglês
出版: 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738380/
https://ncbi.nlm.nih.gov/pubmed/32946773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.08.004
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