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Challenges and Opportunities for Pancreatic Cancer Immunotherapy

Pancreatic ductal adenocarcinoma (PDA) is among the most immune-resistant tumor types. Its unique genomic landscape shaped by oncogenic drivers promotes immune suppression from the earliest stages of tumor inception to subvert adaptive T-cell immunity. Single-agent immune modulators have thus far pr...

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Detalles Bibliográficos
Publicado en:Cancer Cell
Autores principales: Bear, Adham S., Vonderheide, Robert H., O’Hara, Mark H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738380/
https://ncbi.nlm.nih.gov/pubmed/32946773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.08.004
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